| Item Type | Name |
|
Concept
|
Aconitate Hydratase
|
|
Concept
|
Acute Disease
|
|
Concept
|
Actins
|
|
Concept
|
Adenoviridae
|
|
Concept
|
Age Factors
|
|
Concept
|
Administration, Inhalation
|
|
Concept
|
Aorta, Thoracic
|
|
Concept
|
Aortic Valve Stenosis
|
|
Concept
|
Arteries
|
|
Concept
|
Arrhythmias, Cardiac
|
|
Concept
|
Arteriovenous Malformations
|
|
Concept
|
Ankle
|
|
Concept
|
Acetylcholine
|
|
Concept
|
Adaptation, Physiological
|
|
Concept
|
Aftercare
|
|
Concept
|
Calcimycin
|
|
Concept
|
Acetylcysteine
|
|
Concept
|
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
|
|
Concept
|
Algorithms
|
|
Concept
|
Blood Platelets
|
|
Concept
|
Blood Pressure
|
|
Concept
|
Adenosine Triphosphate
|
|
Concept
|
Administration, Oral
|
|
Concept
|
Aerosols
|
|
Concept
|
Antineoplastic Agents
|
|
Concept
|
Bundle-Branch Block
|
|
Concept
|
Energy Intake
|
|
Concept
|
Cell Line, Transformed
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Angina Pectoris
|
|
Concept
|
Aorta
|
|
Concept
|
Chlorides
|
|
Concept
|
Antioxidants
|
|
Concept
|
Cyclohexanols
|
|
Concept
|
Aorta, Abdominal
|
|
Concept
|
Benzamides
|
|
Concept
|
Benzoates
|
|
Concept
|
Atropine
|
|
Concept
|
Dichloroacetic Acid
|
|
Concept
|
Digoxin
|
|
Concept
|
Dithionitrobenzoic Acid
|
|
Concept
|
Biotin
|
|
Concept
|
Barium
|
|
Concept
|
Biopsy, Needle
|
|
Concept
|
Body Weight
|
|
Concept
|
Brachial Artery
|
|
Concept
|
Electrons
|
|
Concept
|
Capsid
|
|
Concept
|
Carbon Monoxide
|
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
|
Concept
|
Cattle
|
|
Concept
|
Cell Separation
|
|
Concept
|
Ischemic Attack, Transient
|
|
Concept
|
Chromosomes, Human, Pair 1
|
|
Concept
|
Cholesterol, Dietary
|
|
Concept
|
Cardiomyopathy, Dilated
|
|
Concept
|
Citric Acid Cycle
|
|
Concept
|
Chicago
|
|
Concept
|
Blood Gas Analysis
|
|
Concept
|
Bradykinin
|
|
Concept
|
Chromium
|
|
Concept
|
Classification
|
|
Concept
|
Cardiotonic Agents
|
|
Concept
|
Creatinine
|
|
Concept
|
Coronary Disease
|
|
Concept
|
Cholesterol
|
|
Concept
|
Contrast Media
|
|
Concept
|
Coronary Artery Disease
|
|
Concept
|
Cytosol
|
|
Concept
|
Diabetes Mellitus, Type 2
|
|
Concept
|
Culture Media
|
|
Concept
|
Iliac Vein
|
|
Concept
|
Dithionite
|
|
Concept
|
Cyanides
|
|
Concept
|
Cytochrome c Group
|
|
Concept
|
Cytoplasm
|
|
Concept
|
Diarrhea
|
|
Concept
|
Diet
|
|
Concept
|
Injections, Intramuscular
|
|
Concept
|
Iron
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Cytochrome P-450 Enzyme System
|
|
Concept
|
Disulfides
|
|
Concept
|
Dithiothreitol
|
|
Concept
|
Cause of Death
|
|
Concept
|
Dogs
|
|
Concept
|
Echocardiography
|
|
Concept
|
Deferoxamine
|
|
Concept
|
Ductus Arteriosus, Patent
|
|
Concept
|
Fluoresceins
|
|
Concept
|
Electrophysiology
|
|
Concept
|
Long QT Syndrome
|
|
Concept
|
Diazooxonorleucine
|
|
Concept
|
Chronic Disease
|
|
Concept
|
Femoral Vein
|
|
Concept
|
Mass Screening
|
|
Concept
|
Cobalt
|
|
Concept
|
Cross-Sectional Studies
|
|
Concept
|
Electron Transport Complex IV
|
|
Concept
|
Disease Susceptibility
|
|
Concept
|
Dobutamine
|
|
Concept
|
Drug Evaluation, Preclinical
|
|
Concept
|
Fluoxetine
|
|
Concept
|
Fatty Acids, Nonesterified
|
|
Concept
|
Ferrous Compounds
|
|
Concept
|
Fibrinogen
|
|
Concept
|
Electric Conductivity
|
|
Concept
|
Electrocardiography
|
|
Concept
|
Environment
|
|
Concept
|
Microtubule-Associated Proteins
|
|
Concept
|
Genes, Dominant
|
|
Concept
|
Fasting
|
|
Concept
|
Fatty Acids
|
|
Concept
|
Fatty Acids, Unsaturated
|
|
Concept
|
Nifedipine
|
|
Concept
|
Forced Expiratory Volume
|
|
Concept
|
Dietary Fats, Unsaturated
|
|
Concept
|
Cyclic GMP
|
|
Concept
|
Health Education
|
|
Concept
|
Heart Diseases
|
|
Concept
|
Heart Failure
|
|
Concept
|
Dopamine
|
|
Concept
|
Ductus Arteriosus
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Liposomes
|
|
Concept
|
Energy Metabolism
|
|
Concept
|
Epithelium
|
|
Concept
|
Enzyme Induction
|
|
Concept
|
Heptanoic Acids
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Infusions, Intravenous
|
|
Concept
|
Mammary Arteries
|
|
Concept
|
Microfilament Proteins
|
|
Concept
|
Mitral Valve Stenosis
|
|
Concept
|
Phenylephrine
|
|
Concept
|
Myocardial Infarction
|
|
Concept
|
Mitosis
|
|
Concept
|
Nitrates
|
|
Concept
|
Platelet-Derived Growth Factor
|
|
Concept
|
Meclofenamic Acid
|
|
Concept
|
Exercise Test
|
|
Concept
|
Extracellular Matrix
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Organ Size
|
|
Concept
|
Muscle, Smooth, Vascular
|
|
Concept
|
NADP
|
|
Concept
|
Glycolysis
|
|
Concept
|
Granulomatous Disease, Chronic
|
|
Concept
|
Oxidative Phosphorylation
|
|
Concept
|
Pancreatic Elastase
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Cricetinae
|
|
Concept
|
Heat-Shock Proteins
|
|
Concept
|
HeLa Cells
|
|
Concept
|
Herpes Simplex
|
|
Concept
|
Pergolide
|
|
Concept
|
Neutrophils
|
|
Concept
|
Laparoscopy
|
|
Concept
|
Oxidation-Reduction
|
|
Concept
|
Cholesterol, HDL
|
|
Concept
|
Mitochondria, Heart
|
|
Concept
|
Phthalimides
|
|
Concept
|
Phospholipases
|
|
Concept
|
Physical Conditioning, Animal
|
|
Concept
|
NAD
|
|
Concept
|
Nitrites
|
|
Concept
|
Oxygen
|
|
Concept
|
Feeding Behavior
|
|
Concept
|
Potassium
|
|
Concept
|
Propionates
|
|
Concept
|
Pre-Excitation Syndromes
|
|
Concept
|
Epoprostenol
|
|
Concept
|
Prostaglandins
|
|
Concept
|
Pulmonary Veins
|
|
Concept
|
Recurrence
|
|
Concept
|
Heart Defects, Congenital
|
|
Concept
|
Research Support as Topic
|
|
Concept
|
Risk Factors
|
|
Concept
|
Pulmonary Heart Disease
|
|
Concept
|
Wolff-Parkinson-White Syndrome
|
|
Concept
|
Rotenone
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Renal Artery
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Serotonin
|
|
Concept
|
Thrombin
|
|
Concept
|
Hematologic Tests
|
|
Concept
|
Silver
|
|
Concept
|
Incidence
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Superoxides
|
|
Concept
|
Training Support
|
|
Concept
|
Intracellular Membranes
|
|
Concept
|
Thrombin Time
|
|
Concept
|
CHO Cells
|
|
Concept
|
Cardiology Service, Hospital
|
|
Concept
|
Ubiquinone
|
|
Concept
|
Hypertrophy, Right Ventricular
|
|
Concept
|
Warfarin
|
|
Concept
|
3',5'-Cyclic-GMP Phosphodiesterases
|
|
Concept
|
Drug Design
|
|
Concept
|
Sex Distribution
|
|
Concept
|
Myocardial Stunning
|
|
Concept
|
Echocardiography, Doppler
|
|
Concept
|
Herpesvirus 1, Human
|
|
Concept
|
Randomized Controlled Trials as Topic
|
|
Concept
|
Cell Culture Techniques
|
|
Concept
|
Radiopharmaceuticals
|
|
Concept
|
Oleic Acid
|
|
Concept
|
rho GTP-Binding Proteins
|
|
Concept
|
rhoB GTP-Binding Protein
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
Ventricular Fibrillation
|
|
Concept
|
S Phase
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Cell Adhesion Molecules
|
|
Concept
|
5,8,11,14-Eicosatetraynoic Acid
|
|
Concept
|
Extracorporeal Membrane Oxygenation
|
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
|
Concept
|
Prevalence
|
|
Concept
|
Papillomavirus Infections
|
|
Concept
|
Exercise
|
|
Concept
|
Fatty Acids, Omega-3
|
|
Concept
|
Ion Channel Gating
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Nisoldipine
|
|
Concept
|
Macrophage Activation
|
|
Concept
|
Mitochondria
|
|
Concept
|
Mitochondria, Muscle
|
|
Concept
|
Infusion Pumps, Implantable
|
|
Concept
|
Chi-Square Distribution
|
|
Concept
|
Gene Expression
|
|
Concept
|
Comorbidity
|
|
Concept
|
N-Acetylgalactosaminyltransferases
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Proto-Oncogene Proteins c-myc
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
RNA Interference
|
|
Concept
|
Age Distribution
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Microtubules
|
|
Concept
|
Cardiomyopathies
|
|
Concept
|
Arachidonic Acid
|
|
Concept
|
Tachycardia, Ventricular
|
|
Concept
|
Efficiency, Organizational
|
|
Concept
|
Patch-Clamp Techniques
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Ventricular Dysfunction
|
|
Concept
|
Impotence, Vasculogenic
|
|
Concept
|
Disease Progression
|
|
Concept
|
Cytochrome P-450 CYP2E1
|
|
Concept
|
Fundoplication
|
|
Concept
|
Basic-Leucine Zipper Transcription Factors
|
|
Concept
|
Inhibitor of Apoptosis Proteins
|
|
Concept
|
Fluorodeoxyglucose F18
|
|
Concept
|
Dietary Sucrose
|
|
Concept
|
Tetraethylammonium
|
|
Concept
|
Romano-Ward Syndrome
|
|
Concept
|
SOXF Transcription Factors
|
|
Concept
|
GTP Phosphohydrolases
|
|
Concept
|
Sirtuin 3
|
|
Concept
|
Fatal Outcome
|
|
Concept
|
Cyclic GMP-Dependent Protein Kinases
|
|
Concept
|
Myofibroblasts
|
|
Concept
|
Microdissection
|
|
Concept
|
MAP Kinase Kinase 4
|
|
Concept
|
Green Fluorescent Proteins
|
|
Concept
|
Proteomics
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Proteasome Endopeptidase Complex
|
|
Concept
|
Endothelin-1
|
|
Concept
|
COS Cells
|
|
Concept
|
Ventricular Dysfunction, Right
|
|
Concept
|
Ryanodine Receptor Calcium Release Channel
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
|
Concept
|
5' Untranslated Regions
|
|
Concept
|
3' Untranslated Regions
|
|
Concept
|
Quality-Adjusted Life Years
|
|
Concept
|
Hydroxymethylglutaryl-CoA Reductase Inhibitors
|
|
Concept
|
rhoA GTP-Binding Protein
|
|
Concept
|
DNA, Intergenic
|
|
Concept
|
Cell-Matrix Junctions
|
|
Concept
|
Nuclear Pore
|
|
Concept
|
Tocopherols
|
|
Concept
|
Evidence-Based Medicine
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Prostaglandins F
|
|
Concept
|
Prostaglandins, Synthetic
|
|
Concept
|
Pulmonary Artery
|
|
Concept
|
Schools, Medical
|
|
Concept
|
Substance P
|
|
Concept
|
Electron Transport Complex I
|
|
Concept
|
Sulfur
|
|
Concept
|
Cytokine Receptor gp130
|
|
Concept
|
PPAR alpha
|
|
Concept
|
Blotting, Western
|
|
Concept
|
STAT2 Transcription Factor
|
|
Concept
|
NF-E2-Related Factor 2
|
|
Concept
|
CDC2 Protein Kinase
|
|
Concept
|
Tetraethylammonium Compounds
|
|
Concept
|
Thallium
|
|
Concept
|
Cyclosporine
|
|
Concept
|
8,11,14-Eicosatrienoic Acid
|
|
Concept
|
Myocardial Ischemia
|
|
Concept
|
Myocardial Reperfusion Injury
|
|
Concept
|
Ion-Selective Electrodes
|
|
Concept
|
Cell Hypoxia
|
|
Concept
|
Survival Rate
|
|
Concept
|
Coronavirus Infections
|
|
Concept
|
Free Radical Scavengers
|
|
Concept
|
Hypoplastic Left Heart Syndrome
|
|
Concept
|
Exercise Tolerance
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Echocardiography, Transesophageal
|
|
Concept
|
Dietary Supplements
|
|
Concept
|
Gene Silencing
|
|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Ventricular Dysfunction, Left
|
|
Concept
|
Diet, Fat-Restricted
|
|
Concept
|
Gadolinium DTPA
|
|
Concept
|
Cation Transport Proteins
|
|
Concept
|
Polypyrimidine Tract-Binding Protein
|
|
Concept
|
Coronary Stenosis
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
History, 20th Century
|
|
Concept
|
Tubulin Modulators
|
|
Concept
|
E2F1 Transcription Factor
|
|
Concept
|
Transcriptome
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
Dynamins
|
|
Concept
|
Pandemics
|
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Cytochromes c
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Actin-Related Protein 2-3 Complex
|
|
Concept
|
Forkhead Transcription Factors
|
|
Concept
|
Cyclic Nucleotide Phosphodiesterases, Type 5
|
|
Concept
|
Growth Differentiation Factor 2
|
|
Concept
|
Drug Discovery
|
|
Concept
|
Cyclin B1
|
|
Concept
|
Diet, High-Fat
|
|
Concept
|
Antibodies, Antinuclear
|
|
Concept
|
Coronary Artery Bypass
|
|
Concept
|
Calcium
|
|
Concept
|
Calcium Channel Blockers
|
|
Concept
|
Cell Line
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Coronary Vessels
|
|
Concept
|
Cyanamide
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Diastole
|
|
Concept
|
Dietary Fats
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Electron Transport
|
|
Concept
|
Epinephrine
|
|
Concept
|
Fetal Hypoxia
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Food Preferences
|
|
Concept
|
Food, Formulated
|
|
Concept
|
Genetic Counseling
|
|
Concept
|
Gestational Age
|
|
Concept
|
Heart Arrest
|
|
Concept
|
Erectile Dysfunction
|
|
Concept
|
Longitudinal Studies
|
|
Concept
|
Lymphocytes
|
|
Concept
|
Membrane Potentials
|
|
Concept
|
Microelectrodes
|
|
Concept
|
Norepinephrine
|
|
Concept
|
Phosphoric Diester Hydrolases
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Receptors, Adrenergic, beta
|
|
Concept
|
Retrospective Studies
|
|
Concept
|
Vitamin A
|
|
Concept
|
Dinoprost
|
|
Concept
|
Cytokines
|
|
Concept
|
Iloprost
|
|
Concept
|
Nucleocapsid
|
|
Concept
|
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
|
|
Concept
|
Okadaic Acid
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Optic Atrophy, Autosomal Dominant
|
|
Concept
|
Kv1.5 Potassium Channel
|
|
Concept
|
Shab Potassium Channels
|
|
Concept
|
Membrane Potential, Mitochondrial
|
|
Concept
|
Atrioventricular Block
|
|
Concept
|
G-Protein-Coupled Receptor Kinase 2
|
|
Academic Article
|
Superoxide dismutase: an antireductant enzyme?
|
|
Academic Article
|
Postischemic oxygen radical production varies with duration of ischemia.
|
|
Academic Article
|
Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
|
|
Academic Article
|
Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity.
|
|
Academic Article
|
The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
|
|
Academic Article
|
Ion channels in the pulmonary vasculature.
|
|
Academic Article
|
Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs.
|
|
Academic Article
|
Utility of a nitric oxide electrode for monitoring the administration of nitric oxide in biologic systems.
|
|
Academic Article
|
Sildenafil: from the bench to the bedside.
|
|
Academic Article
|
Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology.
|
|
Academic Article
|
In memoriam : Francis X. Witkowski.
|
|
Academic Article
|
Alterations in a redox oxygen sensing mechanism in chronic hypoxia.
|
|
Academic Article
|
Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
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Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
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A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent.
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
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Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction.
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Redox control of oxygen sensing in the rabbit ductus arteriosus.
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Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential.
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Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats.
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Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells.
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Academic Article
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Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
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Academic Article
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Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation.
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Coronary nitric oxide production in response to exercise and endothelium-dependent agonists.
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Academic Article
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Triple-bonded unsaturated fatty acids are redox active compounds.
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Voltage-gated potassium channels in human ductus arteriosus.
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Primary pulmonary hypertension: a vascular biology and translational research "Work in progress".
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Case 2. Recurrence of myocardial infarction.
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Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
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The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies.
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Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels.
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
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Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels.
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Innovative strategic Canadian research training from TomorrOw's Research Cardiovascular Health Care Professionals (TORCH).
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Cellular and molecular pathobiology of pulmonary arterial hypertension.
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Academic Article
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Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide.
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Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.
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The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.
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Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
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Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
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Acute oxygen-sensing mechanisms.
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An evidence-based approach to the management of pulmonary arterial hypertension.
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Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling.
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Measurement of endothelial cytosolic calcium concentration and nitric oxide production reveals discrete mechanisms of endothelium-dependent pulmonary vasodilatation.
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Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization.
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Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
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The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
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Images in cardiovascular medicine. Untreated 37-year-old homozygous familial hypercholesterolemic smoker.
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Association of education with dietary intake among young adults in the bi-ethnic Coronary Artery Risk Development in Young Adults (CARDIA) cohort.
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Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.
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The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
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Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
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Enhanced chemiluminescence as a measure of oxygen-derived free radical generation during ischemia and reperfusion.
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The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
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Dilated cardiomyopathy and left bundle branch block associated with ingestion of colloidal gold and silver is reversed by British antiLewisite and vitamin E: the potential toxicity of metals used as health supplements.
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Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells.
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O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.
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Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.
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ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
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Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease.
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Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension.
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Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension.
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Cardiac EASE (Ensuring Access and Speedy Evaluation) - the impact of a single-point-of-entry multidisciplinary outpatient cardiology consultation program on wait times in Canada.
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Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation.
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The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.
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Detection of activated O2 species in vitro and in rat lungs by chemiluminescence.
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A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.
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Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.
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Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species.
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Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies.
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Diagnosis and management of pulmonary hypertension in systemic sclerosis.
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The role of redox changes in oxygen sensing.
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Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.
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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
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A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.
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Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure.
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Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
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Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.
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Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association.
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Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension.
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Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus.
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ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association.
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The association between erectile dysfunction and peripheral arterial disease as determined by screening ankle-brachial index testing.
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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
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Hydroxylamine is a vasorelaxant and a possible intermediate in the oxidative conversion of L-arginine to nitric oxide.
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Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
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Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.
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Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study.
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Oxygen radicals and antioxidant enzymes alter pulmonary vascular reactivity in the rat lung.
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Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.
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Lung ¹8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.
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Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid.
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Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension.
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Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth?
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Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
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The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog.
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Pulmonary endarterectomy surgery--a technically demanding cure for WHO Group IV Pulmonary Hypertension: requirements for centres of excellence and availability in Canada.
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Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells.
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Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease.
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Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
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Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.
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Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension.
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Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
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Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication.
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The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.
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A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward).
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Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
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The WHO classification of pulmonary hypertension: A case-based imaging compendium.
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Evolving epidemiology of pulmonary arterial hypertension.
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Superoxide reduction of a disulfide: a model of intracellular redox modulation?
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Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
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Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells.
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Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells.
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Effects of dietary fish oil on lung phospholipid fatty acid composition and intrinsic pulmonary vascular reactivity.
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Academic Article
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Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
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Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
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Academic Article
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Identification of opioid receptors in the immune system using a novel combination of selective opioid ligands and indirect phycoerythrin immunofluorescence.
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Cellular and molecular basis of pulmonary arterial hypertension.
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Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung.
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The mitochondrion as a Swiss army knife: implications for cardiovascular disease.
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Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension.
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Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension.
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Academic Article
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Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
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Academic Article
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A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension.
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Academic Article
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The measurement of NO in biological systems using chemiluminescence.
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Academic Article
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Potassium channels regulate tone in rat pulmonary veins.
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Academic Article
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Diversity in mitochondrial function explains differences in vascular oxygen sensing.
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Academic Article
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O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor.
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Academic Article
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Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial.
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Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.
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Academic Article
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Hypoxic pulmonary vasoconstriction.
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Usefulness of mean aortic valve gradient and left ventricular diastolic filling pattern for distinguishing symptomatic from asymptomatic patients.
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction.
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A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.
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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
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Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells.
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Academic Article
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ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association.
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A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
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Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report.
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Epigenetic mechanisms of pulmonary hypertension.
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H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells.
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Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks.
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PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
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QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension.
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Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment.
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Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension.
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Academic Article
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FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
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Academic Article
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Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus.
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The role of redox signaling in epigenetics and cardiovascular disease.
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GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
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Differences in food habits and cardiovascular disease risk factors among Native Americans with and without diabetes: the Inter-Tribal Heart Project.
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Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus.
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Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission.
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Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model.
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Academic Article
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Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function.
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Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
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SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
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Academic Article
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Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension.
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Academic Article
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Noninvasive cardiac output measurements in patients with pulmonary hypertension.
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Academic Article
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Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
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Academic Article
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Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.
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Academic Article
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Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients.
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Academic Article
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A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.
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Academic Article
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Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement.
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Academic Article
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Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications.
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Academic Article
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Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension.
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Academic Article
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Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
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Academic Article
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Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
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Academic Article
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Pulmonary arterial hypertension: pathogenesis and clinical management.
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Academic Article
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Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
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Academic Article
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Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012.
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Academic Article
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Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment.
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Academic Article
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Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension.
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Academic Article
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Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.
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Academic Article
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Riociguat for pulmonary hypertension--a glass half full.
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Academic Article
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Mitochondrial dynamics--mitochondrial fission and fusion in human diseases.
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Academic Article
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Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
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Academic Article
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Rodent models of group 1 pulmonary hypertension.
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Academic Article
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Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study.
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Academic Article
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Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.
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Academic Article
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Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
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Academic Article
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Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension.
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Academic Article
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An official American Thoracic Society Statement: pulmonary hypertension phenotypes.
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Academic Article
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Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine.
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Academic Article
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The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease.
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Academic Article
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The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure.
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Academic Article
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Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.
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Academic Article
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Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.
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Academic Article
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Accelerated disulfide reduction with polyunsaturated fatty acids: a mechanism of ionic channel modulation?
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Academic Article
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Mitochondrial fission and fusion in human diseases.
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Academic Article
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[Relevant issues in the pathology and pathobiology of pulmonary hypertension].
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Academic Article
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Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus.
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Academic Article
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Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection.
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Academic Article
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MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
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Academic Article
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Right ventricular adaptation and failure in pulmonary arterial hypertension.
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Academic Article
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Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society.
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Academic Article
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Mitochondrial dynamics in pulmonary arterial hypertension.
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Academic Article
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Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.
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Academic Article
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Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension.
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Academic Article
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Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.
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Academic Article
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The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies.
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Academic Article
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Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension.
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Academic Article
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Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes.
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Academic Article
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A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus.
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Academic Article
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Relevant issues in the pathology and pathobiology of pulmonary hypertension.
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Academic Article
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Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada.
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Academic Article
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A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension.
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Academic Article
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Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
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Academic Article
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Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again.
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Academic Article
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Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease.
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Academic Article
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Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
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Academic Article
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Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities.
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Academic Article
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Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction.
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Academic Article
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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
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Academic Article
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Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
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Academic Article
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Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction".
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Academic Article
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Home Virtual Visits for Outpatient Follow-Up Stroke Care: Cross-Sectional Study.
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Academic Article
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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Academic Article
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Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
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Academic Article
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Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes.
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Academic Article
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An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
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Academic Article
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Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension.
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Academic Article
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Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
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Academic Article
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Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics.
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Academic Article
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Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
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Academic Article
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Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.
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Academic Article
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Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
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Academic Article
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Providing care for the 99.9% during the COVID-19 pandemic: How ethics, equity, epidemiology, and cost per QALY inform healthcare policy.
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Academic Article
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Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
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Academic Article
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Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
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Academic Article
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Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes.
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Academic Article
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Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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Academic Article
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Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice.
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Academic Article
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Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer.
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Academic Article
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Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Academic Article
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Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement.
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Academic Article
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Left Main Coronary Artery Compression in Pulmonary Arterial Hypertension: Percutaneous Treatment to Improve Symptoms.
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Academic Article
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Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension.
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Academic Article
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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
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Academic Article
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Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
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Academic Article
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PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
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Academic Article
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Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop.
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Academic Article
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Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.
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Academic Article
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Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility.
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Academic Article
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Mitochondria in human neutrophils mediate killing of Staphylococcus aureus.
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Academic Article
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Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
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Academic Article
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The comprehensive transcriptome of human ductus arteriosus smooth muscle cells (hDASMC).
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Academic Article
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Anomalous Right Coronary Artery Arising From Distal Left Circumflex Artery.
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Academic Article
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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
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Academic Article
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Using health administrative data to identify patients with pulmonary hypertension: A single center, proof of concept validation study in Ontario, Canada.
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Academic Article
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Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
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Academic Article
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Exertional Dyspnea and Chronotropic Incompetence Caused by Extrinsic Compression of the Right Carotid Body by a Giant Lipoma.
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Academic Article
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SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.
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Academic Article
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An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.
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Academic Article
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A Multi-omic and Multi-Species Analysis of Right Ventricular Failure.
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Academic Article
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Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension.
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Academic Article
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Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension.
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Concept
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Imatinib Mesylate
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Concept
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Venlafaxine Hydrochloride
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Concept
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Forkhead Box Protein O1
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Concept
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NLR Family, Pyrin Domain-Containing 3 Protein
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Concept
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A549 Cells
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Concept
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Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
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Concept
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MCF-7 Cells
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Grant
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O2 sensing in the human and rabbit ductus arteriosus.
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Grant
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The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
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Academic Article
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Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting.
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Academic Article
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Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response.
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Academic Article
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Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus.
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Academic Article
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The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases.
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Academic Article
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Multi-omic and multispecies analysis of right ventricular dysfunction.
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Academic Article
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The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases.
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Academic Article
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Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions.
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Academic Article
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The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes.
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Academic Article
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Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury.
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Academic Article
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Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension.
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Academic Article
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Pulmonary hypertension.
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Academic Article
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Germline and Somatic Mutations in DNA Methyltransferase 3A (DNMT3A) Predispose to Pulmonary Arterial Hypertension (PAH) in Humans and Mice: Implications for Associated PAH.
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